Regenerative Medicine
The Huch Lab: Studies Primary Liver Cancer and Pancreatic cancer, stem cells and tissue regeneration, incorporating 'organoid' technology.
The Vallier Lab: Primarily studies embryonic development in vitro to produce liver and pancreatic cells with the interest in cellular therapies of liver failure and diabetes.
The Laurenti lab: focuses on the study of haemapoietic stem cells (HSC) and progenitor cells with in vitro and in vivo single cell assays, transcriptomics and bioinformatics.
Cancer Research
Jones Group: studies the alteration of normal cell behaviour through mutations in the early stages of cancer evolution
The fitzgerald lab: focuses on early detection and treatment of gastro-oesophageal cancers, aiming to understand the underlying mechanisms, improve upon diagnostic tools and molecular characterisation of oesophageal cancers.
The Huch Lab: Primary Liver Cancer and Pancreatic cancer organoid technology.
Saeb-Parsy Lab: Safety and efficacy of cancer immunotherapies in humanised mouse models.
Transplantation Research:
Saeb-Parsy Lab & Murphy Lab: Ischaemia-reperfusion injury in transplantation
Pettigrew Lab: Is primarily focused on research covering transplant rejection and immune homeostasis
The Bradley lab: is currently in the early stages of modelling human glomerulosclerosis in vitro.
Immunology:
Saeb-Parsy Lab: Currently has projects surrounding the function and immunogenicity of transplanted cellular therapies & the safety and efficacy of cancer immunotherapies in humanised mouse models.
Kosmoliaptsis Lab: Primarily studies histocompatibility and Immunogenetics.
Pettigrew Lab: Transplant rejection and immune homeostasis
Clatworthy Lab: Is focused on Immunoregulation, Immune cell metabolism in kidney/gut.
Jones Lab: Human autoimmunity in relation to recovery during T-cell Lymphopenia.
Genomics:
Human Cell Atlas: aims to create a comprehensive reference maps of all human cells that can be used to define the cellular basis of health and disease
Teichman Group: research focuses on protein structure evolution, higher order protein structure and protein folding. Sarah Teichmen’s research uses genomic approaches to study global regulation of gene expression.
Martincorena Group: research focuses on the accumulation of somatic mutations throughout life.
Diabetes and Obesity:
The Gribble Lab & The Reimann Lab: are currently collaborating to research how gut hormones are released and their actions on target tissues.
Saeb-Parsy Lab: Cryopreservation of multi-cellular aggregates and bioengineered tissues.